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Computational Biology / Bioinformatics II (SS 2003)


Teacher: Thomas Lengauer

Tutor: Niko Beerenwinkel

Language: German

Time and location:

Course: Tuesday and Thursday, 14-16 h, Building 45, Lecture Hall 003.
Starting Thursday, April 24, 2003.
Last lecture Tuesday, July 22, 2003.
First exam: Thursday, July 24, 2003, 13:00-16:00h, Lecture Hall 001
Second exam: Tuesday, October 28, 2003, 9:00-12:00h, room 306, building 36.1
Tutorials: Monday, 9-11 h, Building 45, Room 015 and
Monday, 16-18 h, Building 45, Room 014
starting May 5, 2003.
Office hours:
Thomas Lengauer: after each lecture.
Niko Beerenwinkel: Monday, 11-12 h, Building 46 (MPII), Room 504.


The course is obligatory for bioinformatics students and is targeted towards students in the 4th semester. The course is the sequel to the course 'Bioinformatik I' given by Hans-Peter Lenhof last semester (WS 2002/2003). Students who did not take that course will have to work up on their own some of the basic material on sequence alignment and phylogeny.

Requirements for the course certificate:

Homework assignments will be made available every Thursday on this page. Please return your solutions within one week. For those students who obtain at least 50% of possible points, there will be a written exam at the end of the course period.


The course concentrates on "downstream" problems in computational biology, i.e. those problems that arise after the basic genome and protein sequence has been analyzed. (These latter problems were the focus of the WS 2001/2002 course.) Problems that are covered include protein structure comparison, protein structure prediction, protein domain and protein family analysis, protein function analysis, analysis of protein interactions (docking), drug comparison and drug screening, analysis of mRNA expression data, analysis of metabolic and regulatory networks, analysis of genetic variations, analysis of resistance patterns in infectious diseases.


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Document last changed on Thursday, 13 March 03 - 16:15