Classifier Instance:

Anchor text: NMDA receptor
Target Entity: NMDA_receptor
Preceding Context: Reelin-dependent strengthening of long-term potentiation is caused by ApoER2 interaction with
Succeeding Context: . This interaction happens when ApoER2 has a region coded by exon 19. ApoER2 gene is alternatively spliced, with the exon 19-containing variant more actively produced during periods of activity. According to one study, the hippocampal reelin expression rapidly goes up when there is need to store a memory, as demethylases open up the RELN gene. The activation of dendrite growth by reelin is apparently conducted through Src family kinases and is dependent upon the expression of Crk family proteins, consistent with the interaction of Crk and CrkL with tyrosine-phosphorylated Dab1. Moreover, a Cre-loxP recombination mouse model that lacks Crk and CrkL in most neurons was reported to have the reeler phenotype, indicating that Crk/CrkL lie between DAB1 and Akt in the reelin signaling chain.
Paragraph Title: Receptors
Source Page: Reelin

Ground Truth Types:

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Predicted Types:

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wordnet_person_100007846-2.781146081216755 0
yagoGeoEntity-3.0544830059509906 0
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