Classifier Instance:

Anchor text: Olney's lesions
Target Entity: Olney\u0027s_lesions
Preceding Context: Dextromethorphan has not been shown to cause vacuolization in animals, also known as
Succeeding Context: , despite early speculation that it may, due to similarities with Phencyclidine (PCP) . In rats, however oral administration of dextromethorphan did not cause vacuolization in laboratory tests. Oral administration of dextromethorphan repeatedly during adolescence, however, has been shown to impair learning in those rats during adulthood. The occurrence of Olney's lesions in humans, however, has not been proven or disproven. William E. White, author of the DXM FAQ, has compiled informal research from correspondence with dextromethorphan users suggesting that heavy abuse may result in various deficits corresponding to the brain areas affected by Olney's lesions; these include loss of , decline in ability to learn, abnormalities in some aspects of visual processing, and deficits of abstract language comprehension.
Paragraph Title: Risks associated with use
Source Page: Recreational use of dextromethorphan

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